Faculty and Staff
Larry Schlesinger
Larry Schlesinger
Recent published articles:
·
Carlson
TK, Torrelles JB, Smith K, Horlacher
T, Castelli R, Seeberger
PH, Crouch E, Schlesinger LS. 2009. Critical role of amino acid position 343 of
surfactant protein-D in the selective binding of glycolipids
from Mycobacterium tuberculosis. Glycobiology, no. 19: 1473-1484.
·
Chiu
H-C, Soni S, Kulp SK, Curry
H, Wang D, Gunn JS, Schlesinger LS, Chen C-S. 2009. Eradication of
intracellular Francisella tularensis
in THP-1 human macrophages with a novel autophagy inducing agent. J Biomed Sci., no. 16: 110.
·
Chiu
H-C, Yang J, Soni S, Kulp
SK, Gunn JS, Schlesinger LS, Chen C-S. 2009. Pharmacological exploitation of an
off-target antibacterial effect of the cyclooxygenase-2 inhibitor Celecoxib against Francisella tularensis. Antimicrob Agents and Chemotherapy, no. 53: 2998-3002.
·
Cremer
TJ, Ravneberg DH, Clay CD, Piper-Hunter MG, Marsh CB,
Elton TS, Gunn JS, Amer A, Kanneganti
T-D, Schlesinger LS, Butchar JP, Tridandapani
S. 2009. Mir-155 induction by F. novicida but not the
more virulent F. tularensis, results in enhanced proinflammatory cytokine response. *, no. 4:
e8508.
·
Day
J. Friedman A, Schlesinger LS. 2009. Modeling the immune rheostat of
macrophages in the lung in response to infection. PNAS, no. 106: 11246-11251.
·
Lustberg
M. Schlesinger LS, Mangino J. 2009. Concerns
regarding "Complicated Skin and Skin-Structure Infections and
Catheter-Related Bloodstream Infections: Noninferiority
of Linezolid in a Phase 3 Study. Clinical Infectious Diseases - Letter to the
editor. Vol. 49: 313-314.
·
Premanandan
C, Storozuk C, Clay C, Lairmore
MD, Schlesinger LS, Phipps AJ. 2009. Complement protein C3 binding to Bacillus anthracis spores enhances phagocytosis
by human macrophages. Micro. Pathog..
Vol. 46: 306-314.
·
Sow
FB, Alvarez GR, Gross RP, Satoskar AS, Schlesinger
LS, Zwilling BS, Lafuse WP.
2009. Role of STAT1 and C/EBP? in the macrophage
transcriptional regulation of hepcidin by mycobacterial infection and IFN-?. Journal of Leukocyte Biology, no. 86:
1247-1258.
·
Torrelles
JB, DesJardin LE, MacNeil
J, Kaufman TM, Kutzbach B, Knaup
R, McCarthy TR, Gurcha SS, Besra
GS, Clegg S, Schlesinger LS. 2009. Inactivation of Mycobacterium tuberculosis mannosyltransferase pimB reduces
cell wall lipoarabinomannan and lipomannan
content and increases the rate of bacterial-induced human macrophage cell
death. Glycobiology.
Vol. 19: 743-755.
·
Wang
S-H, Pancholi P. Stevenson K, Yakrus
MA, Butler WR, Schlesinger LS, Mangino JE. 2009.
Pseudo-outbreakk of "Mycobacterium paraffinicum" in a tertiary care medical center. Infections Control and Hospital Epidemiology,
no. 30: 848-853.
·
Carlson
TK; Torrelles JB; Smith K; Horlacher
T; Castelli R; Seeberger
PH; Crouch EC; Schlesinger LS. 2009.Critical role of amino acid
position 343 of surfactant protein-D in the selective binding of glycolipids from Mycobacterium tuberculosis. Glycobiology.
Vol. 19, no. 12. (December 1): 1473.
·
Chiu
HC; Kulp SK; Soni S; Wang
D; Gunn JS; Schlesinger LS; Chen CS. 2009. Eradication of intracellular
Salmonella enterica serovar
Typhimurium with a small-molecule, host cell-directed
agent. Antimicrobial
Agents And Chemotherapy. Vol. 53, no. 12. (December 1): 5236-5244.
·
Clay
CD, Gunn JS, Schlesinger LS. 2010. Antibody-independent classical complement
pathway activation by wildtype and LPS O-antigen
mutant Francisella tularensis
strains. Mol Immun. no.
47: 2245.
·
Mohapatra
NP, Soni S, Rajaram M, Dang
PMC, Reilly TJ, El-Benna J, Schlesinger LS, Gunn JS. Francisella acid phosphatases
inactivate the NADPH oxidase in human phagocytes by dephosphorylation of p47phox and p40phox. J Immunology Epub.
(Forthcoming)
·
Rajaram
MVS, Morris JD, Brooks MN, Torrelles JB, Azad AK,
Schlesinger LS. 2010. Mycobacterium tuberculosis activates human macrophage
PPAR? linking mannose receptor recognition to
regulation of immune responses. J
Immunol. no. 185:
929-942.
·
Torrelles
JB, Schlesinger LS. 2010. Diversity in M. tuberculosis mannosylated
cell wall determinants impacts adaptation to the host. Tuberculosis. no.
90: 84-93.
·
Wang
S-H, Powell DA, Nagaraja HN, Morris JD, Schlesinger
LS, Turner J. 2010. Evaluation of a modified interferon gamma release assay for
the diagnosis of latent tuberculosis infection in adult and pediatric
populations that enables delayed processing. Scandinavian Journal of Infectious Diseases. Epub.
·
Day
J; Schlesinger LS; Friedman A. 2010. Tuberculosis research: going
forward with a powerful "translational systems biology" approach. Tuberculosis (Edinburgh, Scotland). Vol.
90, no. 1 (January 1): 7.
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